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Autoimmunologically mediated syndrome


Autoimmunologically Mediated Syndrome (Lymphocytic Hypophysitis Associated with Dacryoadenitis Syndrome)

General: Lymphocytes infiltrate the hypophysis.

Ocular: Dacryoadenitis.

Clinical: Lymphocytic infiltration of the hypophysis by CD3 cells, T cells, and CD20+ B cells is an autoimmune process that may rarely cause lacrimal gland swelling.

Hirowitz JJ, Rodgers KJA. management of acquired dacryocystitis. Can J Ophthalmol 13:213-216.

Jakobiec FA, Iwanoto T, Knowles DM. Ocular adnexal lymphoid tumors: correlative ultrastructural and immunological markers studies. Arch Ophthalmol 1982; 100:84-98.

Karesh JW, Permank I, Rodriguez MM. Dacryocystitis associated with dacryoadenitis. Arch Ophthalmol 1999; 117: 959-962.

Lee J-H, et al. Lymphocytic hypophysitis: occurrence in two men. Neurosurgery 1994; 43:159-l63.





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