Claude Syndrome (Inferior Nucleus Ruber Syndrome;
Rubro-Spinal-Cerebellar-Peduncle
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General: Paramedian mesencephalic lesion starting in midbrain; often occlusion of terminal branches of the paramedian arteries supplying the inferior portion of the nucleus ruber.
Ocular: Paralysis of ipsilateral oculomotor and trochlear nerves (III, IV).
Clinical: May be associated with motor hemiplegia.
Claude H. Inferior nucleus ruber syndrome. Rev Neurol 1912; 1:311.
Cremieux G, Serratrice G. A case of retraction nystagmus associated with Claude's syndrome. Mars Med (Fre) 1972; 109:635.
Gaymard B, et al. Two mesencephalic lacunar infarcts presenting as Claude's syndrome and pure motor hemiparesis. Eur Neurol 1991; 31:152-l55.
Geeraets WJ. Ocular Syndromes, 3rd ed. Philadelphia: Lea & Febiger, 1976.
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