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Dawson disease (dawson encephalitis; subacute sclerosing panencephalitis; inclusion-body encephalitis)   346


Dawson Disease (Dawson Encephalitis; Subacute Sclerosing Panencephalitis; Inclusion-Body
Encephalitis)& 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp;   & 252g65c nbsp; 

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General: Sclerosing panencephalitis classified as a degenerative, progressive neurologic disorder caused by a measles virus infection of the central nervous system.

Ocular: Nystagmus; ptosis; papilledema; optic neuritis; macular pigmentation and degeneration; focal retinitis; ocular motor palsies; optic atrophy; preretinal vitreous membrane; exophthalmos; visual agnosia; chorioretinitis; retinal vasculitis; macular chorioretinitis.

Clinical: Chronic inflammation of brain with neuronal degeneration; gliosis; eosinophilic inclusion bodies in brain tissue; decline in intellect; behavioral changes; slurred speech; drooling; motor abnormalities; disorientation; seizures; death.

Fenichel GM. Subacute sclerosing panencephalitis. In: Fenichel GM, ed. Clinical Pediatric Neurology, 2nd ed. Philadelphia: WB Saunders, 1993:137.

Gravina RF, et al. Subacute sclerosing panencephalitis. Am J Ophthalmol 1978; 86:106-l09.

Johnston HM, et al. Visual deterioration as presentation of subacute sclerosing panencephalitis. Arch Dis Child 1980; 55:899-90l.

Kovacs B, Vastag O. Fluoroangiographic picture of the acute stage of the retinal lesion in subacute sclerosing panencephalitis. Ophthalmologica 1978; 177:264-269.

Meyer E, et al. Subacute sclerosing panencephalitis: clinicopathological study of the eyes. J Pediatr Ophthalmol Strabismus 1978; 15:19-23.

Miller JR, Jubelt B. Viral infections. In: Rowland LP, ed. Merritt’s Textbook of Neurology, 9th ed. Baltimore: Williams & Wilkins, 1995. Chap. 23, 164-l65.

Miller NR. SSPE. In: Miller NR, ed. Walsh and Hoyt’s Clinical Neuro-Ophthalmology. vol 5, part 2, 4th ed. Baltimore: Williams & Wilkins, 1995:4048-4058.

Salmon JF, et al. Visual loss with dancing extremities and mental disturbances. Surv Ophthalmol 1991; 35:299-306.

Takayama S, et al. Characteristic Clinical features in a case of fulminant subacute sclerosing panencephalitis. Brain Dev 1994; 16:132-l35.

Vignaendra V, et al. Subacute sclerosing panencephalitis with unusual ocular movements: polygraphic studies. Neurology 1978; 28:1052-l056.

Zagami AS, Lethlean AK. Chorioretinitis as a possible very early manifestation of subacute sclerosing panencephalitis. Aust N Z J Med 1991; 21:350-352.




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