Fisher Syndrome (Ophthalmoplegia Ataxia Areflexia Syndrome; Miller-Fisher Syndrome)
General: Acute idiopathic polyneuritis; prognosis good; complete recover 545g64f y over several weeks (variant of Guillain-Barre Syndrome; see Guillain-Barr Syndrome).
Ocular: Moderate ptosis; complete external and almost complete internal ophthalmoplegia; diplopia; sluggish pupil reaction to light; may present without total ophthalmoplegia.
Clinical: Dizziness; severe ataxia; loss of tendon reflexes; chest pains; difficulties in chewing; diminished or absent sense of vibration; upper respiratory tract infection preceding this syndrome.
Fisher M. An unusual variant of acute idiopathic polyneuritis (syndrome of ophthalmoplegia, ataxia and areflexia). N Engl J Med 1956; 255:57.
Igarashi Y, et al. Fisher's syndrome without total ophthalmoplegia. Ophthalmologica 1992; 205:163-l67.
Swick HM. Pseudo internuclear ophthalmoplegia in acute idiopathic polyneuritis (Fisher syndrome). Am J Ophthalmol 1974:77:725.
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