Frankl-Hochwart Syndrome (Pineal-Neurologic-Ophthalmic Syndrome) 4
General: Pineal tumor, usually in early adulthood; poor prognosis.
Ocular: Limitation of upward gaze; concentric field constriction; papilledema; lack of pupillary reaction; nystagmus.
Clinical: Bilateral deafness; ataxia; weakness; headache; vomiting; polydipsia; polyphagia; convulsions; facial paralysis; tremor; Romberg sign; hypertonia; tendon hyperreflexia; Babinski sign.
Magalini SI, Scrascia E. Dictionary of Medical Syndromes, 2nd ed. Philadelphia: JB
Lippincott, 1981.
Von Frankl-Hochwart L. Uber Diagnose der Zirbeldrusen-tumoren. Dtsch Zr Nervenheilkd 1910; 37:455; 1910; 38:309.
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