Kinsbourine syndrome (dancing eyes syndrome; opsoclonus-myoclonus syndrome) 6

General: Etiology unknown; occurs in infancy and early childhood; myoclonic ence 232i89c phalopathy; has been reported as the only manifestation of a postinfectious syndrome without evidence of encephalitis.

Ocular: Twitching of lids and eyebrows on occasion, more pronounced with activity than at rest; irregular vertical movements, jerky in appearance and sometimes with some lateral nystagmic components.

Clinical: Sporadic, jerky movements of head, trunk, and limbs, usually more pronounced when the child is active; lack of coordination; ataxia; irritability; mental retardation; chronic neurologic deficits.

Bhatia K, et al. 'Isolated' postinfectious myoclonus. J Neurol Neurosurg Psychiatry 1992; 55:1089-l091.

Geeraets WI Ocular Syndromes, 3rd ed. Philadelphia: Lea & Febiger, 1976.

Kinsbourine M. Myoclonic encephalopathy of infants. J Neurol Neurosurg Psychiatr 1962; 25:271.

Koh PS, et al. Long-term outcome in children with opsoclonus-myoclonus and ataxia and coincident neuroblastoma. J Pediatr 1994; 125:712-716.

Magalini SI, Scrascia E. Dictionary of Medical Syndromes, 2nd ed. Philadelphia: JB Lippincott, 1981.