Meningococcemia (neisseria meningitides; meningitis) 7

General: Systemic bacterial infection caused by Neisseria meningitides; can be present chronically in patients with immune deficiencies including deficient complement levels.

Ocular: Photophobia; conjunctivitis; chemosis; keratitis; uveitis; panophthalmitis; retinal endophlebitis; macular edema; papillitis; optic neuritis; paresis of sixth or seventh nerve; nystagmus; miosis; hippus; cortical blindness; papilledema (rare); conjunctival petechiae; strabismus.

Clinical: Meningitis; fever; malaise; joint pain; splenic enlargement.

Bannatyne RM. Meningococcal ophthalmia. Can Med Assoc J 1978; 118:769.

Brinser JH, Hess JB. Meningococcal endophthalmitis without meningitis. Can J Ophthalmol 1981; 16:100-l01.

Hanna LS, et al. Ocular complications in meningitis 'fifteen year study.' Metab Pediatr Syst Ophthalmol 1988; 11: 160-l62.

Kilpi T, et al. Length of prediagnostic history related to the course and sequelae of childhood bacterial meningitis. Pediatr Infect Dis J 1993; 12:184-l88.

Miller NR, ed. Walsh and Hoyts Clinical Neuro-Ophthalmology, vol. 5, part 1, 4th ed. Baltimore: Williams & Wilkins, 1995:2983.

Nussbaum E, et al. Primary meningococcal conjunctivitis followed by meningitis. J Pediatr 1978; 92:784-785.