Pemphigus Vulgaris 818d39i 818d39i 818d39i 818d39i 818d39i 818d39i 818d39i 818d39i
General: Primarily in middle-aged people; prognosis varies, from poor to chronic; generalized bullous eruption; blistering autoimmune disease that affects the skin and mucous membranes; association between particular HLA-DR4 and pemphigus vulgaris has been reported.
Ocular: Conjunctival bullae; catarrhal conjunctivitis; scarring and adhesions of conjunctiva.
Clinical: Cutaneous blisters, which may be clear, pustular, or hemorrhagic.
Duane TD, et al. Clinical Ophthalmology. Philadelphia: JB Lippincott, 1987.
McKusick VA. Mendelian Inheritance in Man; A Catalog of Human Genes and Genetic Disorders, 12th ed. Baltimore: The Johns Hopkins University Press, 1998.
Online Mendelian Inheritance in Man, OMIM. McKusick-Nathans Institute for Genetic Medicine, Johns Hopkins University and National Center for Biotechnology Information, National Library of Medicine, February 12, 2007. World Wide Web URL: https://www.ncbi.nlm.nih.gov/omim/.
Scharf SJ, et al. Specific HLA-DQB and HLA-DRB1 alleles confer susceptibility to pemphigus vulgaris. Proc Natl Acad Sci USA 1989; 86:6215-6219.
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