Pigmentary ocular dispersion syndrome (pigmentary glaucoma)

General: Polygenic inheritance; onset at average age 52 years; distribution of pig 323d39d ment in chamber angle; atrophy of posterior iris epithelium; most commonly affects young Caucasian males with myopia; mechanism is likely to be mechanical rubbing between iris pigment epithelium and packets of lens zonules, resulting in aqueous flow obstruction secondary to accumulation of pigment granules in the trabecular meshwork.

Ocular: Myopia; glaucomatous field changes; ocular hypertension; iris translucency; abnormal number of iris processes; insertion of iris anterior to scleral spur; pigmentation of posterior trabecular meshwork, grades 3 to 4; Krukenberg spindles; presence of pigmentation on equatorial border of lens capsule; glaucomatous cupping and myopic optic nerve changes.

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Jabbur NS; Tuli S; Barequet IS, et al. Outsome of laser in situ keratomileusis in patients with pigment dispersion syndrome. J Cataract Refract Surg 2004; 30: 110-l14.

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