Psoriasis (psoriasis vulgaris)

General: Chronic skin disease of unknown etiology; both sex 414j94e es affected; onset at any age; disease peaks at puberty; strong human leukocyte antigen (HLA) association resulting in heritable disease susceptibility.

Ocular: Desquamative psoriatic plaques of lids resulting in madarosis, trichiasis, or ectropion; corneal plaques; xerosis, symblepharon; keratitis; chronic corneal ulceration; phthisis bulbi; iritis.

Clinical: Thick, dry, elevated red patches of skin covered with coarse silvery scales that usually affect areas of skin not exposed to sun, such as scalp, sacrum, elbows, and knees; positive association with Sjgren syndrome and keratitis sicca.

Boss JM, et al. Peripheral corneal melting syndrome in association with psoriasis: a report of two cases. Br Med J (Clin Res) 1981; 282:609-610.

Collins JF. Handbook of Clinical Ophthalmology. New York: Masson, 1982.

Collins P, et al. Psoriasis, psoriatic arthritis and the possible association with Sjogren's syndrome. Br J Dermatol 1992; 126:242-245.

Elder JT, et al. The genetics of psoriasis. Arch Dermatol 1994; 130:216-224.

Fraunfelder FT, Roy FH. Current Ocular Therapy, 5th ed. Philadelphia: WB Saunders, 2000.

Knox DL. Psoriasis and intraocular inflammation. Trans Am Ophthalmol Soc 1979; 77:210-224.

Meyer E, et al. Psoriasis associated with anterior uveitis. J Pediatr Ophthalmol 1977; 14:213-214.