Skew Deviation Syndrome (Hertwig-Magendie Syndrome) 1
General: Vascular deficiency involving the brains 242e42c tem and middle cerebral peduncle; observed after encephalitis, tumors of the cerebellum, and lesions of the labyrinth; this is a vertical strabismus due to a supranuclear lesion; bilateral and alternating skew deviation suggests midbrain or caudal medullar lesion.
Ocular: Alternating paresis of elevators of one eye combined with depressor paresis of the other eye or alternating hyperphorias; in skew deviation the eyes point in diagonally opposite directions; this effect is more pronounced in the eye contralateral to the lesion.
Clinical: Cerebellar ataxia.
Halmagyi GM. Central eye movement disorders. In: Albert DM, Jakobiec FA, eds. Principles and Practice of Ophthalmology, vol. IV. Philadelphia: WB Saunders, 1994:2411.
Keane JR. Alternating skew deviation: 47 patients. Neurology 1985; 35:725.
Miller NR. Walsh and Hoyt's Clinical Neuro-Ophthalmology, 4th ed. Baltimore: Williams & Wilkins, 1987.
Moster ML, et al. Alternating skew deviation on lateral gaze (bilateral abducting hypertropic). Ann Neurol 1988; 23:190.
Silfverskiold BP. Skew deviation in Wallersberg's syndrome. Acta Neurol Scand 1966; 41:381.
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