Spanlang-Tappeiner Syndrome (Keratosis Palmotaris and Corneal Dystrophy Syndrome)
General: Autosomal dominant; e 717j96h tiology unknown; occurs in both sexes; onset age 5 to 20 years; linear palmar and diffuse tar keratosis with dystrophy of the cornea.
Ocular: Corneal opacities (yellowish, tongue-shaped, and not always involving the center of the cornea).
Clinical: Hyperkeratosis of palms and soles; nail dystrophy; hyperhidrosis.
Spanlang H. Beitrage zur Klinik und Pathologie Seltener Hornhauterkrankungen (Dystrophia Adiposo Comeae; Dyskeratosis Comaea Congenitalis). Z Augenheilkd 1927; 62:21.
Thomas CI. The Cornea. Springfield, IL: Charles C. Thomas, 1972.
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