Vogt-Koyanagi-Harada Disease (Harada Disease; Uveitis-Vitiligo-Alopecia-Poliosis Syndrome) 1
General: Viral infection; occurs predominantly among Italian and Japanese individuals; young 727f59h adults; chronic.
Ocular: White lashes; secondary glaucoma; bilateral uveitis; sympathetic ophthalmitis; exudative iridocyclitis; vitreous opacities; bilateral serous retinal detachment and edema with spontaneous reattachment after weeks; depigmentation and patches of scattered pigment later; bilateral acute diffuse exudative choroiditis; papilledema; macular hemorrhage; cataracts; phthisis bulbi; poliosis; scleromalacia; intraocular lymphoma.
Clinical: Poliosis; vitiligo; hearing defect; headache; vomiting; meningeal irritation; reported to occur rarely in children.
Carlson MR, Kerman BM. Hemorrhagic macular detachment in the Vogt-Koyanagi-Harada syndrome. Am J Ophthalmol 1977; 84:632.
Cunningham ET, et al. Vogt-Koyanagi-Harada syndrome in a 4-year old child. Am J Ophthalmol 1995; 120:675-676.
Fraunfelder FT, Roy FH. Current Ocular Therapy, 5th ed. Philadelphia: WB Saunders, 2000.
Ganesh SK, Padmaja MS, Biswas J, et al. Cataract surgery in patients with Vogt-Koyanagi-Harada syndrome. J Cataract Refract Surg 2004; 30: 95-
Manger CC III, Ober RR. Retinal arteriovenous anastomoses in the Vogt-Koyanagi-Harada syndrome. Am J Ophthalmol 1980; 89:186-l91.
Tabbara KF. Scleromalacia associated with Vogt-Koyanagi-Harada syndrome. Am J Ophthalmol 1988; 105: 694-695.
Walker J, et al. Intraocular lymphoma developing in a patient with Vogt-Koyanagi-Harada syndrome. Int Ophthalmol 1993-l994; 17:331-336.
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