Shy-Drager Syndrome (Orthostatic Hypotension Syndrome; Shy-MeGee-Drager Syndrome) 1
General: Etiology unknown; gradual onset; adults; progressive degeneration of the nervous system. 858b14i
Ocular: External ophthalmoplegia; iris atrophy; ocular sympathetic and parasympathetic insufficiency (alternating Homer syndrome, cholinergic supersensitivity, decreased lacrimation, and corneal hypesthesia).
Clinical: Orthostatic hypotension; rigidity; tremor; adiadochokinesia; wasting of muscles; mental retardation; impotence; dysphagia; bilateral vocal cord paralysis; neurogenic bladder; anhydrosis; extremity weakness and paresthesias; dizziness; abnormal postural balance.
Bawa R, et al. Bilateral vocal cord paralysis with Shy-Drager syndrome. Otolaryngol Head Neck Surg 1993; 109: 911-914.
Ohashi N, et al. Otoneurological manifestations of the Shy-Drager syndrome. Eur Arch Otorhinolaryngol 1991; 248: 150-l52.
Rosen J, Brown SI. New ocular signs in Shy-Drager syndrome. Am J Ophthalmol 1974; 78: 1032.
Shy GM, Drager GA. A neurological syndrome associated with orthostatic hypotension. Arch Neurol 1960; 2:511.
Verinder S, et al. Ocular manifestations of Shy-Drager syndrome. Ann Ophthalmol 1982; 14:635-638.
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